The one thing I lamented about the Apple II Plus (vs. the original with Integer BASIC) was that to make room for autostart, they had to rip out the mini-assembler in the Monitor ROM. That was the closest thing I ever saw to an assembly-language REPL before this. At least they were able to keep the disassembler.
I also wish I could select from the completion list with Tab without typing more of the instruction, fish-style. I.e., you press Tab to go through completion 1, completion 2, ..., completion N, completion 1 again with Enter to confirm your pick.
With that said, I love the idea.